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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BRF1
All Species:
18.79
Human Site:
S442
Identified Species:
31.79
UniProt:
Q92994
Number Species:
13
Phosphosite Substitution
Charge Score:
0.31
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92994
NP_001510.2
677
73840
S442
S
S
D
P
K
D
A
S
G
D
G
E
L
D
L
Chimpanzee
Pan troglodytes
XP_510208
819
88957
S584
S
S
D
P
K
D
A
S
G
D
G
E
L
D
L
Rhesus Macaque
Macaca mulatta
XP_001098066
599
65136
L377
D
L
S
G
I
D
D
L
E
I
D
R
Y
I
L
Dog
Lupus familis
XP_548005
637
70371
D415
L
D
L
S
G
I
D
D
L
E
I
D
R
Y
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFK2
676
73781
S441
S
G
D
P
K
D
S
S
G
D
G
E
L
D
L
Rat
Rattus norvegicus
NP_001100231
686
74096
S451
S
G
D
P
K
D
S
S
G
D
G
E
L
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421405
681
75256
T447
D
R
E
P
G
E
N
T
G
D
G
E
L
D
L
Frog
Xenopus laevis
NP_001088063
660
73751
A434
E
Q
E
K
S
D
N
A
G
D
G
E
L
D
L
Zebra Danio
Brachydanio rerio
NP_956183
693
76806
E441
S
I
R
Q
C
I
T
E
T
T
N
V
E
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650616
662
73627
N440
E
L
I
T
D
D
L
N
D
D
E
L
D
Q
Y
Honey Bee
Apis mellifera
XP_623775
648
73504
V426
N
N
S
G
E
I
D
V
A
D
L
D
D
E
E
Nematode Worm
Caenorhab. elegans
NP_495526
759
84015
E440
E
E
D
I
S
D
S
E
I
D
S
Y
I
L
T
Sea Urchin
Strong. purpuratus
XP_794011
768
83924
S509
P
E
E
K
S
P
D
S
D
D
G
E
L
D
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P29056
596
66888
E374
Y
H
E
G
S
E
N
E
T
R
K
R
K
L
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.3
86.4
82.7
N.A.
89.8
81.6
N.A.
N.A.
78.1
72.5
65.9
N.A.
42.5
43.4
32.4
46.3
Protein Similarity:
100
80
87
85.9
N.A.
93.3
86
N.A.
N.A.
87
84.7
77.6
N.A.
59.6
61.7
50
60.1
P-Site Identity:
100
100
13.3
0
N.A.
86.6
86.6
N.A.
N.A.
53.3
53.3
6.6
N.A.
13.3
6.6
20
46.6
P-Site Similarity:
100
100
13.3
20
N.A.
93.3
93.3
N.A.
N.A.
73.3
66.6
13.3
N.A.
20
40
33.3
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
45.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
15
8
8
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
15
8
36
0
8
58
29
8
15
72
8
15
15
50
0
% D
% Glu:
22
15
29
0
8
15
0
22
8
8
8
50
8
15
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
15
0
22
15
0
0
0
43
0
50
0
0
0
0
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
8
8
8
22
0
0
8
8
8
0
8
8
8
% I
% Lys:
0
0
0
15
29
0
0
0
0
0
8
0
8
0
8
% K
% Leu:
8
15
8
0
0
0
8
8
8
0
8
8
50
15
58
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
8
0
0
0
0
22
8
0
0
8
0
0
0
0
% N
% Pro:
8
0
0
36
0
8
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
8
0
0
0
0
0
0
0
0
0
8
0
% Q
% Arg:
0
8
8
0
0
0
0
0
0
8
0
15
8
0
0
% R
% Ser:
36
15
15
8
29
0
22
36
0
0
8
0
0
0
8
% S
% Thr:
0
0
0
8
0
0
8
8
15
8
0
0
0
0
8
% T
% Val:
0
0
0
0
0
0
0
8
0
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
0
8
8
8
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _